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The relationship between exercise and carbohydrate supplementation | How to utilize glycogen to improve endurance and performance
This book explains the important role of carbohydrates (glycogen) during exercise. It covers the energy intake before exercise, the recovery by replenishment of carbohydrates after exercise, the effect of glycogen depletion on endurance and performance, and the effective method of intake.
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The effects of cystine reduce fatigue caused by exercise and maintain energy efficiency
This article explains how the amino acid cystine protects mitochondria and enhances energy production. It also explains how it efficiently converts lipids into energy, reduces oxidative stress during exercise, and helps recover from fatigue and improve endurance.
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Causes of fatigue and tiredness after exercise
Muscles aren't the only cause of fatigue and post-exercise lethargy. Exercise-induced body temperature rises and reduced blood flow to the abdomen can also damage internal organs. We'll also introduce precautions to take in hot and humid environments, as well as how worsening inflammation can lead to decreased performance.
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The effects of alanine and proline help utilize carbohydrate energy to maintain endurance and performance
The amino acids alanine and proline help convert carbohydrates into energy. We explain how they support glycogen utilization during exercise and maintain endurance. We also introduce tips that will help you replenish your energy and maintain your stamina.
The effects of glutamine and the mechanism of fatigue recovery
The mechanism of exercise-induced fatigue and physical damage
Daily exercise is good for staying healthy. However, long-term or strenuous exercise can damage various parts of the body. Well-known symptoms include muscle stiffness and muscle pain, but many people also suffer from body heaviness and fatigue. Let's think about why these problems occur.
Figure 1

The relationship between systemic inflammation and fatigue during exercise
As shown in Figure 1, when we exercise, our body is damaged. Many people are aware that when muscles are damaged, inflammation occurs, causing muscle stiffness and muscle pain. Inflammation is a normal reaction that protects the body and is caused by stress, such as strenuous exercise. However, if the inflammation is too strong, it can cause pain and swelling. In fact, this inflammation does not only occur in the muscles, but throughout the entire body. When inflammation occurs throughout the body, you become more easily fatigued and it becomes difficult to perform at the level you had hoped.1),2).
Also, although it is hard to notice, if you exercise for a long time or too hard, it can also damage your stomach.3).
Damage to the stomach alone is a big problem for athletes, but when such problems occur, inflammation throughout the body can worsen, leading to problems with not being able to perform as well as expected.
The relationship between exercise-induced abdominal damage and general fatigue
Now let's think about what it means to have damage to the stomach.
Hard exercise can also cause damage (inflammation) to the abdomen (stomach, intestines, etc.). In this state, the function of protecting the abdomen is reduced. Exercise can create gaps between the cells lining the intestinal mucosa, allowing foreign substances in the intestine (bacteria and toxins produced by bacteria) to enter the bloodstream. These substances then circulate throughout the body via the blood, worsening inflammation throughout the body (Figure 2).
Figure 2

Abdominal inflammation leads to poor performance
When this happens, your condition will decline, you will tire more easily, and it will be harder to perform at your desired level.
In this way, exercise causes damage to the whole body, damage to the stomach, and the inability to perform as expected. The fatigue that athletes feel all the time may be caused by damage to the stomach. As a result, problems will spread to the whole body, so it is important to take good care of your stomach on a daily basis.
Prevent fatigue with the synergistic effect of two amino acids, "cystine" and "glutamine"
The amino acids "cystine" and "glutamine" prevent the damage suffered by the entire body as explained above (Figure 3).
Figure 3

Antioxidant effect of cystine
"Cystine" is a combination of two cysteines, one of the 20 amino acids that make up the body. It is an amino acid found in large amounts in foods such as chicken, and has the function of protecting us from various stresses.
We investigated the effect of cystine on inflammation caused by oxidative stress. We found that cystine has the effect of suppressing intestinal damage caused by oxidative stress.
Glutamine's role in fatigue recovery and intestinal protection
"Glutamine" is the most abundant amino acid among the 20 types of amino acids. However, it is used in large quantities during hard exercise. It is also known to boost immunity and protect the mucous membranes of the stomach and intestines.
There is data that shows that glutamine suppresses intestinal damage caused by heat stress. It has been found that glutamine has the effect of suppressing intestinal damage caused by heat stress.
Taking "cystine" and "glutamine" together is expected to protect your stomach when doing hard exercise.
Treating stomach and fatigue with "Cystine-Glutamine Mix"
There is data that has examined whether "Cystine-Glutamine Mix" protects the stomach. Adult men were divided into two groups: one group took "Cystine-Glutamine Mix" every day, and another group took a mixture that did not contain this amino acid. The researchers then investigated the damage to the stomach that occurred during exercise (Figure 4).
Figure 4

As a result, the group that consumed food that did not contain amino acids showed damage to the intestinal mucosa caused by exercise and a decrease in the function of protecting the stomach. However, in the group that consumed amino acids, these changes were suppressed. In other words, it was confirmed that taking amino acids has the effect of suppressing damage to the stomach caused by exercise.
Glutamine and cystine prevent fatigue and maintain good physical condition
From the experimental data explained so far, we can see that "Cystine-Glutamine Mix" suppresses the damage to the stomach that occurs during exercise. In other words, by suppressing damage to the entire body and the stomach, it is expected to prevent fatigue caused by a decline in physical condition.
Cystine-Glutamine Mix can help you maintain good condition by incorporating it into your daily care and exercise.







